Research

• “Wharton’s Jelly Mesenchymal Stem Cells: Phenotypic Characterization and Potential in Regenerative Medicine”
  Stem Cell Research & Therapy, 2019
  https://doi.org/10.1186/s13287-019-1223-6

• “Therapeutic Potential of Wharton’s Jelly-Derived Mesenchymal Stem Cells”
  Stem Cells International, 2020
  https://doi.org/10.1155/2020/8859523

Comprehensive review of WJ-MSCs, their anti-inflammatory and immunomodulatory capabilities, and applications across various tissues.

• “Umbilical Cord-Derived Mesenchymal Stem Cells: The New Gold Standard for Cell-Based Therapies?”
  Frontiers in Cell and Developmental Biology, 2020
  https://doi.org/10.3389/fcell.2020.00784

Discusses UC-MSCs advantages over adult stem cells, especially for clinical use.

• “Intra-articular Injection of Umbilical Cord-Derived Mesenchymal Stem Cells for the Treatment of Knee Osteoarthritis: A Phase I/II Clinical Trial”
  Stem Cells Translational Medicine, 2016
  https://doi.org/10.5966/sctm.2015-0245

Demonstrated safety and early efficacy in using UC-MSCs for knee OA patients.

• “Wharton’s Jelly-Derived Mesenchymal Stem Cells for Cartilage Regeneration in Osteoarthritis: A Systematic Review and Meta-analysis”
  Journal of Translational Medicine, 2021
  https://doi.org/10.1186/s12967-021-02795-3

Meta-analysis confirms promising outcomes for WJ-MSCs in reducing pain and improving mobility.

• “Human Umbilical Cord-Derived Mesenchymal Stem Cell-Conditioned Media Promotes Hair Growth Through the Activation of Hair Follicle Dermal Papilla Cells”
  Stem Cells International, 2021
  https://doi.org/10.1155/2021/6691249

Demonstrated improved hair follicle activity and hair regeneration using umbilical cord-derived factors.

• “Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Promote Hair Regeneration via the Wnt/β-Catenin Pathway”
  Stem Cell Research & Therapy, 2020
  https://doi.org/10.1186/s13287-020-01707-2

Highlights how UC-MSC exosomes trigger signaling pathways essential to follicle growth.

• “Wharton’s Jelly-Derived Mesenchymal Stem Cells Promote Skin Regeneration and Wound Healing”
  International Journal of Molecular Sciences, 2020
  https://doi.org/10.3390/ijms21155479

Showed improved healing, skin remodeling, and collagen formation in wound sites.

• “Stem Cell-Derived Exosomes in Skin Regeneration: A Novel Therapeutic Strategy for Cutaneous Wounds and Aging Skin”
  Cells, 2020
  https://doi.org/10.3390/cells9092146
• “Exosome Therapy in Dermatology: A Review”
  Journal of Dermatological Treatment, 2022
  https://doi.org/10.1080/09546634.2021.2008789

Discusses aesthetic benefits of stem cell-derived exosomes (including UC source) for anti-aging and dermatologic applications.

• “Immunomodulatory Effects of Umbilical Cord-Derived Mesenchymal Stem Cells: Implications for Inflammatory Disease Therapies”
  Cell Death & Disease, 2020
  https://doi.org/10.1038/s41419-020-2430-4

• “Umbilical Cord-Derived Stem Cells in Regenerative Medicine”
  Transfusion and Apheresis Science, 2021
  https://doi.org/10.1016/j.transci.2021.103067
  

WJ-MSCs shown to reduce inflammatory markers and regulate immune responses—ideal for degenerative and autoimmune conditions.